Anaphylaxis to polyethylene glycol ingestion is well recognized. Copied below for your convenience is a very extensive case report as well as a reference to another such report. Unfortunately as you can see from reading the first case, polyethylene glycols are somewhat ubiquitous and very difficult to avoid. Polyethylene glycol (PEG compounds) PEGs are widely used in cosmetics as thickeners, solvents, softeners, and moisture-carriers. Depending on manufacturing processes, PEGs may be contaminated with measurable amounts of ethylene oxide and 1,4-dioxane, which are both carcinogens. Normal use of these products is not dangerous or toxic to the skin or airways. However, prolonged or excessive application can cause redness and itching to sensitive skin. Ingestion of propylene glycol could cause irritation, burning sensations to the throat and mouth, nausea and vomiting. The pharmacokinetics of methoxy polyethylene glycol-epoetin beta were studied in 64 pediatric patients with CKD (ages 5 to 17 years) who were on hemodialysis and who were previously receiving another ESA (epoetin alfa/beta or darbepoetin alfa). At steady state (following the third intravenous...